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Catherine M. Polizzi, Ph.D.

Partner | Palo Alto

My passion is protecting complex, cutting–edge biotech and pharma innovations as they emerge from laboratories to commercialization, ultimately reaching millions of people around the world.

Experience

The world’s first and most successful biotechnology company, has relied on Catherine’s strategic patent counseling and prosecution services for its most difficult and challenging patent matters for nearly 15 years. Her work involves developing overall patent strategy, patent application drafting, and prosecution for key technologies. Her high-value work for Genentech also includes strategic assessment of key and novel technologies, as well as patent litigation support and advisement.

A biotechnology company developing forefront gene sequencing technology used in scientific research, turns to Catherine to serve as lead patent counsel related to in situ and spatial assay platforms for cellular and subcellular identification of cell and biomarker diversity in tissues, including gene expression, gene sequencing, RNA profiling, and related reagents, panels, hardware, and software analysis tools.

A biotechnology company that specializes in enzyme engineering, focusing on improving sustainability and cost-efficiency of manufacturing in the pharmaceutical industry, including in the manufacture of oligonucleotides and small molecule drugs, relies on Catherine for developing Codexis’s complex IP strategy. She has provided critical advice in management of their intellectual property portfolio, including strategic consideration of patent application filings, and patent risks to their planned commercial operations, including freedom to operate.

Juno Therapeutics has relied on Catherine for patent strategy and prosecution from its very beginning. Juno is one of the best-funded startups in biotechnology history. It went on to become a publicly traded company in 2014 and ultimately was acquired by Celgene in 2018 for $9 billion; the strength of the patent portfolio that Catherine crafted helped drive the valuation for the deal. She led the IP team on the acquisition.

Celgene calls on Catherine for its patent strategy, drafting, and IP due diligence matters. She worked with Abraxis BioScience for many years in a similar capacity to help develop their IP position for the highly successful cancer drug, Abraxane. Catherine then counseled the company through its $2.9 billion acquisition by Celgene Corporation, including providing significant IP strategy and due diligence counseling. This IP platform was a major component of the valuation of the company.

Dewpoint Therapeutics engaged Catherine to lead its patent strategy from the very beginning. Dewpoint is on the cutting edge of drug discovery, with technology relating to condensate biology, a new and paradigm-shift area of drug development. Catherine led the IP strategy and due diligence for its partnership with Bayer to research new treatments for cardiovascular and gynecological diseases. The work that Dewpoint is doing is seen as a significant move forward in the biopharma industry and opens the door to many potential new discoveries in biology through biomolecular condensates. For example, in January 2021, Dewpoint teamed up with Pfizer to develop new treatments for a rare kind of muscular dystrophy. In July 2020, Dewpoint announced its collaboration with Merck to evaluate a novel approach for the treatment of HIV.

Frontier Medicines, a clinical-stage precision medicine company advancing treatments for genetically defined patient populations in oncology and immunology, has entrusted all aspects of patent strategy and portfolio development for its pipeline of small molecule therapeutics to Catherine.

Insitro, a multibillion-dollar startup pharmaceutical drug company, turned to Catherine to develop its global IP stategy. The company is at the forefront of advancing AI and data-driven drug discovery and development, and trusted Catherine to manage the company’s portfolio.

Sonoma Biotherapeutics, a clinical-stage biopharmaceutical company that is developing cell therapies that use engineered regulatory T cell therapies to treat serious autoimmune and inflammatory diseases, called on Catherine to direct its patent strategy and development.

Additional representative clients include clinical-stage and startup companies, such Aimmune Therapeutics, Alpine Immune Sciences, Botanical Solution, Cartography Biosciences, CohBar, Corner Therapeutics, Cytokinetics, Dynavax Technologies, Enveda Therapeutics, Frazier Life Sciences, GOA Therapeutics, Immunome, Indapta Therapeutics, Larkspur Biosciences, Lyndra Therapeutics, Maze Therapeutics, Myst Therapeutics, Nanoprobes, Ollin Biosciences, Passkey Therapeutics, Prelude Therapeutics, Sana Biotechnology, Sangamo Therapeutics, Seagen (formerly Seattle Genetics), Sirenas, Syntis Bio, Tacit Therapeutics, TARIS Biomedical, The Immune Co., Turnstone Biologics, and Volastra Therapeutics.


Patent Strategy Attorney of the Year – California

LMG Life Sciences Americas Awards 2025