Sam A. LoCascio

Scientific Analyst | San Diego

slocascio@mofo.com | (858) 314-7791

slocascio@mofo.com
(858) 314-7791

An MIT-trained neuroscientist with over 10 years of experience in academic, clinical, and industry settings, Dr. Sam LoCascio focuses his work on patent drafting and prosecution, with prior research experience in neurobiology, stem cell biology, immunology, and genome engineering.

Prior to joining the firm, Sam was an A.P. Giannini Postdoctoral Research Fellow at the University of California, Los Angeles. At UCLA, he applied cutting-edge sequencing and brain-mapping technologies to identify gene mutations affecting neural circuit assembly. Sam earned his Ph.D. in neuroscience from the Massachusetts Institute of Technology (MIT), where he developed and patented methods for genome engineering and uncovered new mechanisms of stem cell-mediated brain regeneration.

During his doctoral studies, Sam performed research at the Broad Institute of MIT and Harvard, and was a National Defense Science and Engineering Graduate (NDSEG) research fellow at the Whitehead Institute for Biomedical Research. Prior to graduate school, Sam was a research associate at Harvard Medical School, where he investigated bone marrow transplantation as a path to immune tolerance.

He received his B.S. in biology, summa cum laude, from Emmanuel College, Boston. As an undergraduate student, he interned at Merck, where he characterized alleles affecting Alzheimer’s disease in neuronal cell lines for drug screen development.

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